Join our Bioprocess Development (BPD) team within the R&D department, pioneering the future of sustainable food production. We are focusing on optimising large-scale cell culture processes for cultivated beef.
We are seeking a highly motivated associate/Jr. Bioprocess Engineer to derive the optimisation and scale-up for our core cell culture process. The successful candidate will be a hands-on expert in continuous cultivation, focusing heavily on enhancing perfusion culture efficiency and developing robust fed-batch strategies for high-density mammalian cell growth.
Your key responsibilities
- Process Optimisation: Design, execute, and analyze experiments in bioreactors (bench-scale and pilot-scale) aimed at optimising critical process parameters for mammalian cell perfusion culture.
- Perfusion Enhancement: Deepen understanding and optimise continuous cell culture systems utilising Tangential Flow Filtration (TFF) and/or Alternating Tangential Flow (ATF) technology to maximise cell viability, density, and nutrient utilisation.
- Fed-Batch Development: Taking part in the development and optimisation of scalable fed-batch process strategies, including nutrient media design, feeding regimes, and process control logic.
- Troubleshooting: Systematically investigate bioreactor performance issues, harvest challenges, and filtration problems, develop root-cause analyses, and implement corrective actions.
- Data Analysis and Reporting: Analyze complex experimental data, and clearly document findings in technical reports and internal presentations.
- SOP Development: Draft and revise Standard Operating Procedures (SOPs) and batch records related to bioreactor operation and maintenance.
- Collaboration: Work closely with upstream scientists, analytical chemists, and the facilities/engineering teams.
